KnotesFree Orthopaedic & FRCS notes, viva stations and higher order SBAs

Painful TKA

Must KnowKneethinKbox SBA

Clinical image

AP radiograph of a knee prosthesis showing Knee Society radiographic zones

AP radiograph of a knee prosthesis showing Knee Society radiographic zones. Source: Wikimedia Commons — Mikael Häggström, M.D.; CC0 1.0. Image binary is embedded locally in this package; original source and licence are retained.

Key points

Talking the talk

  • AP and Lateral radiograph showing PS TKA. Both components appear well fixed. My primary concern is an area of subchondral lucency under the medial tibial component. I will suspect infection unless otherwise proved but will rule out other causes of painful TKA
  • Causes of painful tka are Intrinsic, extrinsic and Infection
  • I will take a detailed history and examination stressing on
    • the primary indication,
    • post operative course including leaking wounds,
    • pattern of pain,
    • Health of scar and
    • the skin condition and
    • instability.

Causes

  • Infection
  • Intrinsic causes: AIMS and 3 Fractures
    • Aseptic loosening
    • Instability
    • Malalignment
    • Stiffness, soft tissue impingement
    • Patellar problems
    • Extensor mechanism rupture
    • Periprosthetic fracture
    • Implant breakage
  • Extrinsic causes
    • Hip pathology
    • Neurologic
      • Spine Pathology
      • CRPS
    • Vascular
    • Unexplained 1%

Aseptic loosening

  • Decreased joint space
  • Radiolucency

Instability

  • ML
  • AP
  • F/E

Malalignment

  • Sagital
  • coronal
  • Rotational

CFA: Coronal femoral component angle, CTA: coronal TC angle

Soft tissue impingement

  • Component overhang
  • Patellar clunk
  • Popliteal tendon impingement
  • Fabellar impingement

Overhang

Clung syndrome

History

  • Preop
  • Indications
  • Pain
  • Expectations
  • Depression and anxiety
  • Wound problems

Symptoms

  • Pain
  • Swelling
  • Stiffness
  • Instability

Pain

  • Unchanged (never felt right)
  • Sharp catch (impingement)
  • Painful to touch (CRPS)
  • Start up pain (Aseptic loosening)
  • Getting down stairs (PF)

C/E

  • Gait (Thrust)

  • Skin: inflammation, sinus, atrophy (CRPS)

  • Effusion

  • Hip

  • Tenderness

  • PF

  • Medial: overhang, pes anserina

  • PM: Popliteus

  • Cutaneous neuroma

  • ROM

  • PF joint

  • Spin hip and foot and ankle, NV

Inv

  • xray: AP, Lateral, skyline
    • Alignment
    • Loosening
    • Wear of PE
    • Overhanging
    • Joint line
    • Fractures

CT

  • Malrotation

Bone scan

  • Good negative

Lab

  • FBC
  • ESR >30 (3 mo post op)
  • CRP> 10(3 weeks)
  • IL 6 > 10pico gram

Syovial fluid aspiration

  • All painful knee
  • Gram
  • WBC >3000 a/c, 10000 in c/c
  • 2 weeks no Ab
  • Leukocyte esterases
  • Alfa defincin

PJI

  • Approach
    • Difficult problem
    • Local bone infection unit
    • MDT
  • 1-2%

Key points

AAOS GUIDELINE for KNEE

  • Test ESR (75% Sn, 70 % Sp) , CRP (88 and 74)
  • IL 6 (97 and 91)
  • Aspirate
  • Tissue culture: 3-6 using different instruments from diff areas
  • No Ab until after culture
  • No Gram stain inta operative
  • Nuclear imaging

Classification

  • a/c: <3 weeks
  • c/c: >3 weeks

Management

  • Biofilm

    • A polysaccaride film ( glycocalyx)
    • improves bacterial nutrition
    • Reduce access of Ab to bacteria
  • DAIR: < 3 WEEKS

  • 2 stage revision

    • gold std
    • 1st stage: debride, spacer, ab for 6 weeks
    • 2nd stage:> 5 weeks( CRP and culture neg)

Others

  • Single stage
  • Long term Ab suppression
  • Arthrodesis
  • Amputation/disarticulation

2 vs 1 stage

  • Jamsen et al: equal functional result with better infection eradication in 2 stage
  • Buechel et al: 90% infection eradication with 1 stage

Written/reviewed by Kishore Puthezhath

Professor of Orthopaedics and Consultant Paediatric Orthopaedic Surgeon

FRCS (Tr & Orth) revision resource

Reviewed: September 2026