KnotesFree Orthopaedic & FRCS notes, viva stations and higher order SBAs

Radiation effects on bone

High YieldApplied Basic SciencesthinKbox SBA

Effects on tissues

Ionising radiation impairs cellular viability, vascularity and healing potential.

Orthopaedic consequences

  • Osteopenia
  • Growth disturbance in children
  • Delayed union or non-union
  • Soft-tissue fibrosis
  • Osteoradionecrosis
  • Pathological fracture
  • Radiation-induced sarcoma after latency in rare cases

Surgical implications

  • Poor soft tissues and poor healing
  • Increased infection risk
  • Need for careful fixation and biological augmentation in selected cases

Diagram

Radiation effects on bone

Written/reviewed by Kishore Puthezhath

Professor of Orthopaedics and Consultant Paediatric Orthopaedic Surgeon

FRCS (Tr & Orth) revision resource

Reviewed: September 2026