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First CMC Joint Osteoarthritis

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Presentation

Basal thumb osteoarthritis causes:

  • pain at the base of the thumb
  • weakness of pinch and grip
  • difficulty opening jars or turning keys
  • adduction deformity in advanced disease
  • compensatory MCP hyperextension

Examination

Look for swelling and deformity, then palpate the first CMC joint. Axial loading with circumduction can reproduce pain but should be interpreted with the rest of the examination.

Assess:

  • first web-space contracture
  • MCP hyperextension
  • STT joint symptoms
  • de Quervain disease as a differential

Imaging

Standard thumb/hand radiographs show joint-space loss, osteophytes, subchondral sclerosis and subluxation. Radiographic severity does not perfectly predict symptoms.

Radiographs can stage structural disease but correlate imperfectly with symptoms. Treatment should be driven by pain and function.

Non-operative treatment

  • activity modification

  • splinting

  • analgesia

  • hand therapy

  • intra-articular corticosteroid injection for selected patients

  • education and activity adaptation

  • analgesia

  • splintage

  • hand therapy

  • injection in selected patients

Surgical options

For persistent disabling symptoms:

  • trapeziectomy with or without soft-tissue reconstruction
  • first CMC arthrodesis in selected younger high-demand patients
  • implant arthroplasty in selected settings

The key objectives are pain relief and functional pinch, not simply restoration of radiographic anatomy.

Associated MCP hyperextension may require simultaneous treatment when it compromises thumb function.

Clinical pattern

Thumb-base OA commonly causes pain with pinch and grip.

Symptoms include:

  • pain at the first CMC joint
  • weakness opening jars or turning keys
  • difficulty with pinch
  • progressive deformity

Examine for:

  • local tenderness
  • crepitus/grind
  • subluxation
  • MCP hyperextension
  • thenar function

Biomechanics

The saddle-shaped CMC joint allows wide thumb movement but experiences high forces during pinch. Ligament insufficiency and cartilage degeneration can permit metacarpal subluxation and progressive deformity.

MCP hyperextension may develop as compensation.

Surgery

When symptoms remain substantial despite non-operative care, options include:

  • trapeziectomy alone
  • trapeziectomy with ligament/tendon procedures
  • suspension techniques
  • arthrodesis in selected high-demand cases
  • implant arthroplasty in selected settings

No single operation is ideal for every patient.

Associated deformity

If MCP hyperextension is substantial, it may require separate treatment to restore a stable pinch posture.

FRCS synthesis

The aim is pain relief with a stable, mobile thumb and useful pinch. Radiographic stage alone should not dictate surgery.

Written/reviewed by Kishore Puthezhath

Professor of Orthopaedics and Consultant Paediatric Orthopaedic Surgeon

FRCS (Tr & Orth) revision resource

Reviewed: September 2026