KnotesFree Orthopaedic & FRCS notes, viva stations and higher order SBAs

Infected THA

Must KnowHipthinKbox SBA

Clinical image

Temporary hip spacer used in treatment of an infected hip arthroplasty

Temporary hip spacer used in treatment of an infected hip arthroplasty. Source: Wikimedia Commons — Hellerhoff; CC BY-SA 4.0. Image binary is embedded locally in this package; original source and licence are retained.

Key points

  • This is the supine AP front view of the left hip showing a cemented THA.
  • What concerns me is the radiolucencies seen in the Gruen zones 1,2,4, and 7. The acetabulum looks well fixed but there is suspect lucent zone in charnley zone 3. I would like to see the immediate post operative X-ray to know whether the stem has sunk and latest lateral view of left hip.

What do you think?

  • The prosthesis appears loose. It was inserted only 3 years back. The radiographs are highly suggestive of infection until proven otherwise.
  • I would take a thorough history covering the reason for the procedure, any leaking wound after surgery, UTI, chest infection or dental extraction, immunosuppressive comorbidities and smoking. I wound examine for signs of inflammation, health of the scar and do Full blood count, ESR and CRP
  • I will aspirate the hip if the pretest probability is high, especially if ESR and CRP are elevated.

Causes

  • Pre operative
  • Per operative
  • Post operative

Preoperative

  • Potential septic lesions
  • Comorbidities
  • Admission: better is same day
  • Separation from trauma
  • Preparation: better is in anaesthetic room

Peroperative

  • Antibiotic prophylaxis
  • Surgical technique
  • Attire and behaviour
    • Movement in theatre
    • Ace Mask
    • Weaved pattern gowns
    • 2 pair gloves
    • No hair exposed
    • Body exhaust system
    • Disposable non woven drapes
  • Theatre and ventilation

Postoperative

  • Catheter with antibiotic cover
  • Special surgical ward
  • Hand hygiene

Investigations

  • FBC
  • ESR
  • CRP
  • IL6
  • Xray
  • Bone scan
  • Do not routinely aspirate (only if pretest probability is high)

Management

  • Long term antibiotic suppression
    • Elderly unfit patient
  • DAIR
    • Healthy patient
    • Known organism
    • Stable component
    • Skin and soft tissue good
  • Single stage revision (Butchholz 77% success rate)
  • Two stage revision (6 weeks delay) Norvegian registry 94% success

Single stage

Advantages Disadvantages
One operation Prolonged procedure
Mobility Ab Sensitivity should be known
No disuse atrophy Ab cement must
Reduce cost Bone loss is C/I

Two stage revision

Advantages Disadvantage
Adequate debridement More morbidity
Appropriate Ab can be given Prolonged rest and disuse atrophy
Better assessment of infection control Increased cost
Allows uncemented 2nd surgery more complicated
Allows BG Less functional outcome

PROSTALAC

  • Maintain soft tissue
  • Delivers high conc of antibiotic
  • Maintain LL
  • Articulating spacer helps partial/full weight bearing

Salvage

  • Resection
  • Arthrodesis
  • Amputation

Written/reviewed by Kishore Puthezhath

Professor of Orthopaedics and Consultant Paediatric Orthopaedic Surgeon

FRCS (Tr & Orth) revision resource

Reviewed: September 2026