Foot and Ankle
Morton’s Neuroma Foot and Ankle
Definition
Compressive neuropathy of the interdigital nerve
Epidemiology
Women > Men – likely shoewear related
Aetiology
Shoewear – narrow toe box and high heels (squeezes spaces together)
Bursal Hypertrophy causes compression
Position:
Most common in 3rd space (between 3rd and 4th toes)
Then 2nd space , followed by 4th space
4th space uncommon, 1st space virtually unheard of
Think again if these areas are affected
Symptoms
Pain – well-localised to area
Worse on weight-bearing, especially in high heels
Burning or numb sensation around toes
Signs
Pain on palpation between plantar MT spaces
Mulder’s Click
Click felt while palpating on volar aspect and squeezing MTs
Painful click felt
Imaging
XR
Screening for other causes of metatarsalgia-type pain
USS & MRI
Both potentially useful, but diagnosis is clinical
MRI has a high false-positive rate
USS is user-dependent – may not change management
Management
Non-Operative
Works for the majority
Activity modification
Shoewear alteration – avoid heels or narrow toe boxes
Metatarsal bar to offload forefoot
Steroid Injection
Can work permanently
Probably most accurate under USS guidance
Diagnostic and therapeutic value
Surgical
Commonly through a longitudinal incision in IM space
Nerve lies deep to Transverse Metatarsal Ligament (TMTL)
Surgical Steps:
Divide TMTL
Dissect nerve
Key: Excise nerve and all its fibres just proximal to the bifurcation and a few centimetres proximal to web space
Send for histology to confirm you have excised the original neuroma
Minimises risk of neuroma formation
Results
80-85% cure rate
Improved by correct patient selection
Complications
Primary complication is recurrence – neuroma formation
Usually due to insufficiently proximal nerve resection
Related FRCS revision notes Written/reviewed by Kishore Puthezhath
Professor of Orthopaedics and Consultant Paediatric Orthopaedic Surgeon
FRCS (Tr & Orth) revision resource
Reviewed: September 2026
Core revision references: Miller's Review of Orthopaedics; Campbell's Operative Orthopaedics; Orthobullets . Current specialty guidelines are linked within individual notes where applicable.
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